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How much weight can I lose on Mounjaro, Wegovy or Ozempic?
For people already prescribed GLP-1 medication. Weight Easy does not prescribe, sell or arrange medication. Your prescriber makes treatment and dose decisions.
By the Weight Easy Editorial Team ·
✓ Free to download
Quick answer: In the main trials, people lost an average of 15% to 21% of their body weight on tirzepatide (Mounjaro, Zepbound) over 72 weeks and about 15% on semaglutide 2.4 mg (Wegovy) over 68 weeks. People with type 2 diabetes lost less, about 9% to 15%. Enter your details to get your week-by-week projection in the free Weight Easy app.
Weekly injections
- Mounjaro (tirzepatide)
- Zepbound (tirzepatide)
- Ozempic (semaglutide)
- Wegovy (semaglutide)
- Generic semaglutide for diabetes (Obeda, Sematrinity, GLIPIQ)
- Generic semaglutide for weight (Noveltreat)
- Yurpeak (tirzepatide)
- Compounded semaglutide
- Compounded tirzepatide
- Trulicity (dulaglutide)
- Bydureon BCise (exenatide extended-release)
Daily injections
- Saxenda (liraglutide)
- Victoza or generic liraglutide
- Byetta (exenatide)
Daily tablets
- Wegovy pill (oral semaglutide)
- Rybelsus 1.5, 4 or 9 mg, or Ozempic tablets (oral semaglutide)
- Rybelsus 3, 7 or 14 mg (oral semaglutide)
- Foundayo (orforglipron)
The dose your prescriber plans to keep you on, and the trial it comes from.
Fill in the form to see your result
Still needed: your medication, whether you have type 2 diabetes, your planned maintenance dose, your starting weight.
Works with: Mounjaro, Zepbound, Ozempic, Wegovy, Wegovy pill, Rybelsus, Ozempic tablets, Saxenda, Victoza, Trulicity, Bydureon BCise, Byetta, Foundayo, Yurpeak, Obeda, Noveltreat, Semaglyn, Sematrinity, GLIPIQ, compounded semaglutide, compounded tirzepatide.
Free to download
See if you're on track, week by week
Log your weight in Weight Easy and see your own trend over weeks, not days. When progress slows, ask Weight Easy's AI coach what to change, from protein to questions worth asking your doctor.
- Weight and waist trends over weeks
- Weekly check-ins that ignore daily noise
- Protein and muscle tips from a dietitian-built plan
- Ask Weight Easy's AI coach about a plateau any time
Free to download. Subscription for full features, with a 7-day free trial on the yearly plan. For people already prescribed GLP-1 medicine. Weight Easy does not prescribe, sell or arrange medicine. Follow the treatment instructions from your prescribing clinician.
Read the complete guide
The calculator stays free on this page. Its longer explanatory article, medicine-specific FAQ and cited sources live in the Weight Easy blog, alongside the other health and tracking guides.
Read the guide and FAQ →Related guides
- Mounjaro Results Timeline: What to ExpectUnderstand typical timelines and factors that may influence weight loss results when using Mounjaro as part of your treatment.
- Wegovy Results Timeline: What to ExpectLearn about typical timelines and early changes when using Wegovy, along with factors that may influence weight loss progress.
- How Much Weight Can You Lose on Ozempic? Realistic ExpectationsGet an overview of typical weight loss results when using Ozempic and what to expect during treatment.
- GLP-1 Weight Loss Plateau: Why It Happens and What to DoUnderstand why weight loss plateaus occur with GLP-1 treatments and explore practical approaches to address these stalls in progress.
Sources and limits
- STEP 1, Wilding et al., NEJM 2021; STEP 2, Davies et al., Lancet 2021; STEP UP, Lancet Diabetes Endocrinol 2025.
- SURMOUNT-1, Jastreboff et al., NEJM 2022; SURMOUNT-2, Garvey et al., Lancet 2023; SURMOUNT-5, NEJM 2025.
This tool is for education. It does not diagnose, prescribe or change a dose. Always follow your prescriber and the leaflet that came with your medication.